By public transport:

See here for current bus and timetables.

By car:

From the Brenner Pass: from the motorway A22 take the “Bozen-Süd” exit then proceed via the South Tyrolean Wine Route to Kaltern
From the South: from the motorway A22 take the “Neumarkt-Auer-Tramin” exit then proceed via the South Tyrolean Wine Route to Kaltern
From Arlberg/Landeck: via the Reschenpass to Meran, take the expressway to the “Eppan” exit then proceed via the South Tyrolean Wine Route to Kaltern

Parking:

The South Tyrolean Wine Museum is located in the centre of Kaltern (pedestrian area from April to October).
It is just a few minutes on foot from the Trutsch (P3), Sölva (P4) and Rottenburgerplatz (P5) car parks.
Bus parking is located on the Rottenburgerplatz (P5) parking area and in the Kellereistrasse (P1).